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Sarah J. Tsai, MD, FRCPC

TitlePediatric Endocrinologist
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address2401 Gilham Rd
Kansas City MO 64108
ORCID ORCID Icon0000-0002-7693-5676 Additional info
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    Other Positions
    TitleAssistant Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    Memorial University of Newfoundland, St. John NL, CanadaMD2005
    Memorial University of Newfoundland, St. John NL, CanadaResidency2008Pediatrics
    Children's Hospital of Eastern, University of Ottawa, Ontario Ottawa, CanadaFellowship2011Pediatric Endocrinology

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Dr. Tsai has made significant strides in the area of clinical research during her early career at Children’s Mercy/UMKC. She has served as the Assistant Director of Clinical Research in the Division of Endocrinology for the past 6 years. She obtained an internal grant in 2012 from the Cross Foundation which led to a randomized control trial of motivational interviewing in adolescents with type 1 diabetes. This complex study was successfully completed with a high retention rate. The results of this study have been presented at the American Diabetes Association. She published a paper regarding out study methodology. She led the development of a new pediatric diabetes knowledge test (M-WIKAD), which is a validated measure of diabetes knowledge in Adolescents with Type 1 Diabetes. The research team presented M-WIKAD at the prestigious International Society for Pediatric and Adolescent Diabetes (ISPAD) conference in Australia in 2015, which is an international pediatric diabetes conference. The measure was recently published in a peer-reviewed journal.

    Dr. Tsai has been productive in the area of adrenal insufficiency. She was invited to Canada to present her team’s discovery of a founder effect in the province of Newfoundland. Specifically, they identified a novel variant of the StAR protein resulting in a less severe phenotype of congenital lipoid adrenal hyperplasia. The adrenal research working group at CMH has also recently published a paper in which they describe their recent finding that morning cortisol levels vary with sex and pubertal status.

    Dr. Tsai has served as a primary investigator on a pharmaceutical study. She has been a subinvestigator on numerous multicenter clinical trials. She earned designation as a Certified Principal Investigator (CPI) via the Association of Clinical Research Professionals.

    She has authored 11 peer reviewed manuscripts (8 as first author) since she began working at CMH and published 9 abstracts. She has reviewed numerous manuscripts for high quality journals. She has supervised several medical student, pediatric resident and fellow research projects.

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Patria Alba, Sarah Tsai, Naim Mitre. The Severity of Growth Hormone Deficiency does not Predict the Presence or Absence of Brain Magnetic Resonance Imaging Abnormalities – A Retrospective Review in European Endocrinology. 2020.
    2. Jacob SA, Williams DD, Boyd J, Dileepan K, Tsai SL. Variations in Morning Serum Cortisol Levels Based on Sex and Pubertal Status. Horm Res Paediatr. 2019; 92(3):162-168. PMID: 31851964.
      View in: PubMed
    3. Sarah L Tsai, Susana R Patton, Stephen DeLurgio, David D Williams, Kavitha Dileepan, Alexander Karmazin, Melinda Storm, Mark A Clements. A NEW PAEDIATRIC DIABETES KNOWLEDGE TEST – M-WIKAD DEVELOPMENT AND FACTOR ANALYSIS. European Endocrinology. 2019; 1(15).
    4. Tsai SL, Clements MA, Apodaca TR. Reflections on Incorporating a Behavioral Intervention into a Busy Pediatric Subspecialty Clinic. J Pediatr Health Care. 2017 May - Jun; 31(3):404-408. PMID: 27692505.
      View in: PubMed
    5. Tsai SL, Green J, Metherell LA, Curtis F, Fernandez B, Healey A, Curtis J. Primary Adrenocortical Insufficiency Case Series: Genetic Etiologies More Common than Expected. Horm Res Paediatr. 2016; 85(1):35-42. PMID: 26650942.
      View in: PubMed
    6. Apodaca TR, Tsai SL, Miller MK, Maddux MH, Kennedy D, Trowbridge K. Implementing motivational interviewing in a pediatric hospital. Mo Med. 2014 May-Jun; 111(3):212-6. PMID: 25011343.
      View in: PubMed
    7. Tsai SL, Laffan E. Congenital Growth Hormone Deficiency - A Review with a Focus on Neuroimaging. Eur Endocrinol. 2013 Aug; 9(2):136-140. PMID: 29922370.
      View in: PubMed
    8. Tsai SL, Seiler KJ, Jacobson J. Morning cortisol levels affected by sex and pubertal status in children and young adults. J Clin Res Pediatr Endocrinol. 2013; 5(2):85-9. PMID: 23748059.
      View in: PubMed
    9. Tsai SL, Laffan E, Lawrence S. A retrospective review of pituitary MRI findings in children on growth hormone therapy. Pediatr Radiol. 2012 Jul; 42(7):799-804. PMID: 22763804.
      View in: PubMed
    10. Tsai SL, Ahmet A. Treatment with methimazole in a 3-year-old male with thyroid hormone resistance. Horm Res Paediatr. 2012; 77(6):402-6. PMID: 22538421.
      View in: PubMed
    11. Tsai SL, Hadjiyannakis S, Nakhla M. Hyperglycemic hyperosmolar syndrome at the onset of type 2 diabetes mellitus in an adolescent male. Paediatr Child Health. 2012 Jan; 17(1):24-6. PMID: 23277751.
      View in: PubMed
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