 RNA, Long Noncoding
"RNA, Long Noncoding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.
| Descriptor ID |
D062085
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| MeSH Number(s) |
D13.444.735.790.375
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| Concept/Terms |
RNA, Long Noncoding- RNA, Long Noncoding
- Noncoding RNA, Long
- lncRNA
- Long ncRNA
- ncRNA, Long
- RNA, Long Non-Translated
- Long Non-Translated RNA
- Non-Translated RNA, Long
- RNA, Long Non Translated
- Long Non-Coding RNA
- Long Non Coding RNA
- Non-Coding RNA, Long
- RNA, Long Non-Coding
- Long Non-Protein-Coding RNA
- Long Non Protein Coding RNA
- Non-Protein-Coding RNA, Long
- RNA, Long Non-Protein-Coding
- Long Noncoding RNA
- RNA, Long Untranslated
- Long Untranslated RNA
- Untranslated RNA, Long
- Long ncRNAs
- ncRNAs, Long
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Below are MeSH descriptors whose meaning is more general than "RNA, Long Noncoding".
Below are MeSH descriptors whose meaning is more specific than "RNA, Long Noncoding".
This graph shows the total number of publications written about "RNA, Long Noncoding" by people in this website by year, and whether "RNA, Long Noncoding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 2 | 0 | 2 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Long Noncoding" by people in Profiles.
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de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ, Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. 2021 05 13; 184(10):2633-2648.e19.
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Cohen ASA, Simotas C, Webb BD, Shi H, Khan WA, Edelmann L, Scott SA, Singh R. Haploinsufficiency of the basic helix-loop-helix transcription factor HAND2 causes congenital heart defects. Am J Med Genet A. 2020 05; 182(5):1263-1267.
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Talebizadeh Z, Shah A, DiTacchio L. The potential role of a retrotransposed gene and a long noncoding RNA in regulating an X-linked chromatin gene (KDM5C): Novel epigenetic mechanism in autism. Autism Res. 2019 07; 12(7):1007-1021.
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Caron M, St-Onge P, Drouin S, Richer C, Sontag T, Busche S, Bourque G, Pastinen T, Sinnett D. Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes. PLoS One. 2018; 13(11):e0207250.
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Li R, Fang L, Pu Q, Bu H, Zhu P, Chen Z, Yu M, Li X, Weiland T, Bansal A, Ye SQ, Wei Y, Jiang J, Wu M. MEG3-4 is a miRNA decoy that regulates IL-1? abundance to initiate and then limit inflammation to prevent sepsis during lung infection. Sci Signal. 2018 06 26; 11(536).
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Ramsay L, Marchetto MC, Caron M, Chen SH, Busche S, Kwan T, Pastinen T, Gage FH, Bourque G. Conserved expression of transposon-derived non-coding transcripts in primate stem cells. BMC Genomics. 2017 02 28; 18(1):214.
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Qian P, He XC, Paulson A, Li Z, Tao F, Perry JM, Guo F, Zhao M, Zhi L, Venkatraman A, Haug JS, Parmely T, Li H, Dobrowsky RT, Ding WX, Kono T, Ferguson-Smith AC, Li L. The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell. 2016 Feb 04; 18(2):214-28.
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Shechner DM, Hacisuleyman E, Younger ST, Rinn JL. Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display. Nat Methods. 2015 Jul; 12(7):664-70.
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Younger ST, Kenzelmann-Broz D, Jung H, Attardi LD, Rinn JL. Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Res. 2015 May 19; 43(9):4447-62.
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Alml?f JC, Lundmark P, Lundmark A, Ge B, Pastinen T, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syv?nen AC. Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. PLoS One. 2014; 9(7):e102612.
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