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Barbara A. Pahud, MD, MPH

TitleDirector of Research, Infectious Diseases
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address2401 Gillham Rd
Kansas City MO 64108
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    Other Positions
    TitleStaff Physician
    InstitutionChildren's Mercy Kansas City
    DepartmentPediatrics

    TitleAssociate Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics

    TitleClinical Associate Professor of Pediatrics
    InstitutionUniversity of Kansas Medical Center
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    La Salle University, Mexico City, MexicoMD2000
    Columbia University, New York, NYMPH2003Population and Family Health
    Infants and Children’s Hospital of Brooklyn Maimonides Medical Center, Brooklyn, NYResidency2006Pediatrics
    Stanford University Medical Center, Stanford, CAFellowship2007Stanford-LPCH Vaccine Program
    University of California, San Francisco, CAFellowship2010Pediatric Infectious Diseases
    Center for Disease Control and Prevention Stanford University Medical Center, Stanford, CAFellowship2010Vaccine Safety
    Collapse awards and honors
    2010Special Recognition Award, National Institute of Allergy and Infectious Diseases, Division of Microbiology and Infectious Dise
    2010Advance Course in Vaccinology Selected Participant, Fondation Mérieux
    2012Global Vaccine Advocacy Event Selected Participant, American Academy of Pediatrics
    2012Young Investigator Coaching Program, Society for Pediatric Research
    2013Nominated for Daniel Scagliotti Teaching Award, Educator of the Year, University of Missouri, Kansas City
    2014Selected for participation in the first Genomic Medicine Master Class , Children’s Mercy Hospital
    2016Selected as a Member, Society for Pediatric Research
    2017Division Teaching Award, Infectious Diseases Division , Children’s Mercy Hospital
    2017Teamwork Appreciation, Division of Pediatrics Faculty Award, Children’s Mercy Hospital
    2019EMBO Laboratory Leadership for Group Leaders Selected Participant, Stowers Institute for Medical Research
    2019 - 2020Presidential Engagement Fellows Program, University of Missouri System
    2019International Trainer of Vaccine Hesitancy , International Pediatric Association
    2020 - PresCouncil on Health Policy – Advisory Commission on Childhood Vaccines (ACCV) , Health Resources and Services Administration (HRSA) - Department of Health and Human Services (HHS)

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Dr. Pahud is a pediatric infectious diseases physician who has spent her career focusing on vaccine preventable diseases, immunization development, safety, and efficacy, vaccine education for physicians and healthcare workers, and addressing vaccine hesitancy.

    In addition to contributing to the fields of vaccines, she has also contributed to developing pediatric research overall through various partnerships and collaborations in academia, industry, and the federal government. As a result, she has extensive experience participating in multi-center collaborations and implementing clinical trials.
    Collapse research activities and funding
         Jul 1, 2008 - Jun 30, 2010
    Center for Disease Control and Prevention (CDC)
    Clinical Immunization Assessment Network (CISA)
    Role Description: Vaccine Safety Fellowship

    1U01lP001057-01     (Selvarangan)Aug 1, 2011 - Aug 31, 2021
    Center for Disease and Control Prevention (CDC) and National Institute of Allergy and Infectious Diseases (NIAID)
    Prospective active surveillance for acute gastroenteritis and acute respiratory illness in children.
    Role Description: The goal of this study is to evaluate rotavirus vaccine effectiveness and determine the epidemiology of acute gastroenteritis in children to identify and advice on vaccines for enteric diseases.
    Role: Co-Investigator

         Jan 1, 2014 - Dec 31, 2014
    Center for Disease Control and Prevention (CDC)
    Chapter HPV Immunization Rate Improvement Grant
    Role: PI

    27980301     (Pahud)Aug 1, 2016 - Jul 1, 2018
    Pfizer Independent Grants for Learning, Pfizer Foundation
    Collaboration for Vaccination Research and Education (CoVER)
    Role Description: The overall purpose of this project is to develop and implement a Collaboration for Vaccination Education and Research (CoVER) to increase pediatric and FM residents, knowledge and competency for communicating with patients and patients, families about vaccination in order to decrease the incidence of vaccine preventable diseases and decrease gaps in vaccine coverage.
    Role: PI

    UG1HD090849-01     (Pahud)Sep 21, 2016 - Aug 31, 2020
    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Sunflower Pediatric Clinical Trials Research Extension (SPeCTRE)
    Role Description: The goal of SPeCTRE is to improve the opportunity for children in rural and underserved areas of Kansas and neighboring states to participate in clinical trials. We will conduct outreach, education, and engagement activities that will extend clinical trials participation opportunities, which will help to support the development of better care options for children.
    Role: PI

    HHSN2722013000201; Task Order: HSN27200009-FY2017.     (Pahud)Nov 1, 2016 - Jul 31, 2017
    National Institute for Allergy and Infectious Diseases (NAIAD)
    Protocol Development: A Phase II Trial to Evaluate the Safety and Efficacy of Trimethoprim Sulfamethoxazole vs. Standard of Care Antimicrobials for Pediatric Osteomyelitis
    Role Description: The purpose of this work is to design a clinical trial in collaboration with Division of Microbiology and Infectious Diseases, NIAID, NIH, DHHS - Vaccine and Treatment Evaluation Unit (DMID-VTEU) to determine whether PO transition therapy using TMP-SMX is non-inferior to standard of care antimicrobials for uncomplicated pediatric acute hematogenous osteomyelitis. This work will result in DMID Protocol Number: 16-0100 for implementation.
    Role: PI

    NICHD-2011-POP01     (Pahud)May 16, 2018 - Sep 21, 2020
    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Pharmacokinetics of Understudied Drugs Administered to Children per Standard of Care (POPs)
    Role Description: This project aims to characterize the pharmacokinetics (PK) of understudied drugs administered to children per standard of care as prescribed by their treating caregiver.
    Role: PI

    1R01HD093628-01A1     (Pahud)Sep 10, 2018 - Jul 31, 2019
    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Presumptively Initiating Vaccines and Optimizing Talk (PIVOT)
    Role Description: Evaluation of the Presumptively Initiating Vaccines and Optimizing Talk with Motivational Interviewing (PIVOT with MI) Intervention.
    Role: PI

    UM1AI068632     (Pahud)May 1, 2019 - Apr 30, 2022
    National Institute of Allergy and Infectious Diseases (NIAID) and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    IMPAACT 2021 RSV Study
    Role Description: Randomized Phase I/II Study of the Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ?NS2/?1313/I1314L, RSV 6120/?NS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age.
    Role: PI

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Salamanca de la Cueva I, Pahud B, Huang LM, Leonardi M, Garcia-Sicilia J, Céspedes J, Abdelnour A, Tamura T, Kuroki H, Chiu NC, Virta M, Kokko S, Horn M, Panzer F, Kim JH, Jin L, Moerman L, Debacq C, Parra J, Ugarte A, Bi D. Immunogenicity and safety of porcine circovirus-free human rotavirus vaccine in healthy infants: a phase III, randomized trial. J Infect Dis. 2020 May 04. PMID: 32365189.
      View in: PubMed
    2. Williams S, Clark S, Humiston S, Pahud B, Middleton D, Lewis KO. Identifying Medical Residents’ Perceived Needs in Vaccine Education though a Needs Assessment Survey. AMEE MedEdPublish Journal. 2020.
    3. Williams S, Clark S, Humiston S, Pahud B, Middleton d, Lewos KO. Determining the instructional effectiveness of online vaccine education modules: a focus-group analysis. AMEE MedEdPublish Journal. 2019.
    4. Otto WR, Pahud BA, Yin DE. Pediatric Mucormycosis: A 10-Year Systematic Review of Reported Cases and Review of the Literature. J Pediatric Infect Dis Soc. 2019 Sep 25; 8(4):342-350. PMID: 31181136.
      View in: PubMed
    5. Munoz FM, Anderson EJ, Bernstein DI, Harrison CJ, Pahud B, Anderson E, Creech CB, Berry AA, Kotloff KL, Walter EB, Atmar RL, Bellamy AR, Chang S, Keitel WA. Safety and immunogenicity of unadjuvanted subvirion monovalent inactivated influenza H3N2 variant (H3N2v) vaccine in children and adolescents. Vaccine. 2019 Aug 23; 37(36):5161-5170. PMID: 31375440.
      View in: PubMed
    6. Harrison CJ, Weldon WC, Pahud BA, Jackson MA, Oberste MS, Selvarangan R. Neutralizing Antibody against Enterovirus D68 in Children and Adults before 2014 Outbreak, Kansas City, Missouri, USA1. Emerg Infect Dis. 2019 03; 25(3):585-588. PMID: 30789123.
      View in: PubMed
    7. Kotloff KL, Shirley DT, Creech CB, Frey SE, Harrison CJ, Staat M, Anderson EJ, Dulkerian S, Thomsen IP, Al-Hosni M, Pahud BA, Bernstein DI, Yi J, Petrikin JE, Haberman B, Stephens K, Stephens I, Oler RE, Conrad TM. Mupirocin for Staphylococcus aureus Decolonization of Infants in Neonatal Intensive Care Units. Pediatrics. 2019 01; 143(1). PMID: 30587533.
      View in: PubMed
    8. Pahud BA, Williams SE, Lee BR, Clark S, Lewis KO, Middleton D, Humiston S. Knowledge, Attitudes, Confidence, and Hesitancy Toward Vaccines Among Residents in Pediatric and Family Practice Programs. Open Forum Infectious Diseases. 2018; 5(Suppl1):S740.
    9. Wheat J, Myint T, Guo Y, Kemmer P, Hage C, Terry C, Azar MM, Riddell J, Ender P, Chen S, Shehab K, Cleveland K, Esguerra E, Johnson J, Wright P, Douglas V, Vergidis P, Ooi W, Baddley J, Bamberger D, Khairy R, Vikram HR, Jenny-Avital E, Sivasubramanian G, Bowlware K, Pahud B, Sarria J, Tsai T, Assi M, Mocherla S, Prakash V, Allen D, Passaretti C, Huprikar S, Anderson A. Central nervous system histoplasmosis: Multicenter retrospective study on clinical features, diagnostic approach and outcome of treatment. Medicine (Baltimore). 2018 03; 97(13):e0245. PMID: 29595679.
      View in: PubMed
    10. Widdice LE, Hoagland R, Callahan ST, Kahn JA, Harrison CJ, Pahud BA, Frey SE, Berry AA, Kotloff KL, Edwards KM, Mulligan MJ, Sudman J, Nakamura A, Bernstein DI. Caregiver and adolescent factors associated with delayed completion of the three-dose human papillomavirus vaccination series. Vaccine. 2018 03 07; 36(11):1491-1499. PMID: 29428177.
      View in: PubMed
    11. Widdice LE, Unger ER, Panicker G, Hoagland R, Callahan ST, Jackson LA, Berry AA, Kotloff K, Frey SE, Harrison CJ, Pahud BA, Edwards KM, Mulligan MJ, Sudman J, Bernstein DI. Antibody responses among adolescent females receiving two or three quadrivalent human papillomavirus vaccine doses at standard and prolonged intervals. Vaccine. 2018 02 01; 36(6):881-889. PMID: 29306506.
      View in: PubMed
    12. Pahud B, Pallotto EK. Rotavirus Immunization for Hospitalized Infants: Are We There Yet? Pediatrics. 2018 01; 141(1). PMID: 29212882.
      View in: PubMed
    13. Bradley JS, Blumer JL, Romero JR, Michaels MG, Munoz FM, Kimberlin DW, Pahud B, DeBiasi RL, Yamamoto G, Roberts G, Hossain M, Shortino D, Yates PJ, Adams B, Peppercorn A. Intravenous Zanamivir in Hospitalized Patients With Influenza. Pediatrics. 2017 Nov; 140(5). PMID: 29051331.
      View in: PubMed
    14. Williams SE, Lewis LO, Lee B, Humiston S, Middleton D, Clark S, Pahud BA . Needs Assessment for Resident Education Within the Collaboration for Vaccine Education and Research (CoVER). Open Forum Infectious Diseases. 2017; 4(suppl1):S441-S442.
    15. Butler D, Torres-Torres S, Pahud B, Myers A, Bass JA, St Peter SD, McCulloh R. Clostridium difficile Ileitis in Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2017 06; 64(6):e156-e158. PMID: 25611030.
      View in: PubMed
    16. Phuong LK, Bonetto C, Buttery J, Pernus YB, Chandler R, Felicetti P, Goldenthal KL, Kucuku M, Monaco G, Pahud B, Shulman ST, Top KA, Trotta F, Ulloa-Gutierrez R, Varricchio F, de Ferranti S, Newburger JW, Dahdah N, Singh S, Bonhoeffer J, Burgner D. Kawasaki disease and immunisation: A systematic review. Vaccine. 2017 03 27; 35(14):1770-1779. PMID: 28259442.
      View in: PubMed
    17. Schuster JE, Selvarangan R, Hassan F, Briggs KB, Hays L, Miller JO, Pahud B, Puls HT, Queen MA, Thompson MT, Weddle G, Jackson MA. Clinical Course of Enterovirus D68 in Hospitalized Children. Pediatr Infect Dis J. 2017 03; 36(3):290-295. PMID: 28187115.
      View in: PubMed
    18. Wallace GS, Pahud BA, Weldon WC, Curns AT, Oberste MS, Harrison CJ. Seroprevalence of poliovirus antibodies in the Kansas City metropolitan area, 2012-2013. Hum Vaccin Immunother. 2017 04 03; 13(4):776-783. PMID: 28059613.
      View in: PubMed
    19. Phuong LK, Bonetto C, Buttery J, Pernus YB, Chandler R, Goldenthal KL, Kucuku M, Monaco G, Pahud B, Shulman ST, Top KA, Ulloa-Gutierrez R, Varricchio F, de Ferranti S, Newburger JW, Dahdah N, Singh S, Bonhoeffer J, Burgner D. Kawasaki disease and immunisation: Standardised case definition & guidelines for data collection, analysis. Vaccine. 2016 12 12; 34(51):6582-6596. PMID: 27863715.
      View in: PubMed
    20. Williams SE, Pahud BA, Price L, Arora T, Kelly S, Tuell D. A Systematic Approach to Develop a Vaccine Safety and Vaccine Hesitancy Curriculum. Academic Pediatrics. 2016; 16(6):29.
    21. Fulbright JM, Williams SE, Pahud BA. Immune Thrombocytopenic Purpura Following Postexposure Rabies Prophylaxis. J Pediatr Hematol Oncol. 2016 Mar; 38(2):165. PMID: 26808372.
      View in: PubMed
    22. Libster R, McNeal M, Walter EB, Shane AL, Winokur P, Cress G, Berry AA, Kotloff KL, Sarpong K, Turley CB, Harrison CJ, Pahud BA, Marbin J, Dunn J, El-Khorazaty J, Barrett J, Edwards KM. Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules. Pediatrics. 2016 Feb; 137(2):e20152603. PMID: 26823540.
      View in: PubMed
    23. Pahud BA, Ault KA. The Expanded Impact of Human Papillomavirus Vaccine. Infect Dis Clin North Am. 2015 Dec; 29(4):715-24. PMID: 26610422.
      View in: PubMed
    24. Fulbright JM, Williams SE, Pahud BA. A Case of Immune Thrombocytopenic Purpura After Rabies Vaccination. J Pediatr Hematol Oncol. 2015 Oct; 37(7):e427-8. PMID: 26165405.
      View in: PubMed
    25. Felicetti P, Trotta F, Bonetto C, Santuccio C, Brauchli Pernus Y, Burgner D, Chandler R, Girolomoni G, Hadden RD, Kochhar S, Kucuku M, Monaco G, Ozen S, Pahud B, Phuong L, Bachtiar NS, Teeba A, Top K, Varricchio F, Wise RP, Zanoni G, Živkovic S, Bonhoeffer J. Spontaneous reports of vasculitis as an adverse event following immunization: A descriptive analysis across three international databases. Vaccine. 2016 12 12; 34(51):6634-6640. PMID: 26392009.
      View in: PubMed
    26. Bonetto C, Trotta F, Felicetti P, Alarcón GS, Santuccio C, Bachtiar NS, Brauchli Pernus Y, Chandler R, Girolomoni G, Hadden RD, Kucuku M, Ozen S, Pahud B, Top K, Varricchio F, Wise RP, Zanoni G, Živkovic S, Bonhoeffer J. Vasculitis as an adverse event following immunization - Systematic literature review. Vaccine. 2016 12 12; 34(51):6641-6651. PMID: 26398442.
      View in: PubMed
    27. Pahud B, Clark S, Herigon JC, Sherman A, Lynch DA, Hoffman A, Jackson MA. A pilot program to improve vaccination status for hospitalized children. Hosp Pediatr. 2015 Jan; 5(1):35-41. PMID: 25554757.
      View in: PubMed
    28. Halsey NA, Griffioen M, Dreskin SC, Dekker CL, Wood R, Sharma D, Jones JF, LaRussa PS, Garner J, Berger M, Proveaux T, Vellozzi C, Broder K, Setse R, Pahud B, Hrncir D, Choi H, Sparks R, Williams SE, Engler RJ, Gidudu J, Baxter R, Klein N, Edwards K, Cano M, Kelso JM. Immediate hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines: reports to VAERS. Vaccine. 2013 Dec 09; 31(51):6107-12. PMID: 24120547.
      View in: PubMed
    29. Weddle G, Pahud B, Jackson MA. Mucormycosis after a tornado in Joplin, Missouri. N Engl J Med. 2013 03 14; 368(11):1066-7. PMID: 23484843.
      View in: PubMed
    30. Pahud BA, Williams SE, Dekker CL, Halsey N, Larussa P, Baxter RP, Klein NP, Marchant CD, Sparks RC, Jakob K, Aukes L, Swope S, Barnett E, Lewis P, Berger M, Dreskin SC, Donofrio PD, Sejvar JJ, Slade BA, Gidudu J, Vellozzi C, Edwards KM. Clinical assessment of serious adverse events in children receiving 2009 H1N1 vaccination. Pediatr Infect Dis J. 2013 Feb; 32(2):163-8. PMID: 23334340.
      View in: PubMed
    31. Poli F, Overeem S, Lammers GJ, Plazzi G, Lecendreux M, Bassetti CL, Dauvilliers Y, Keene D, Khatami R, Li Y, Mayer G, Nohynek H, Pahud B, Paiva T, Partinen M, Scammell TE, Shimabukuro T, Sturkenboom M, van Dinther K, Wiznitzer M, Bonhoeffer J. Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation. Vaccine. 2013 Jan 30; 31(6):994-1007. PMID: 23246545.
      View in: PubMed
    32. Weddle G, Gandy K, Bratcher D, Pahud B, Jackson MA. Apophysomyces trapeziformis infection associated with a tornado-related injury. Pediatr Infect Dis J. 2012 Jun; 31(6):640-2. PMID: 22301481.
      View in: PubMed
    33. Pahud BA, Rowhani-Rahbar A, Glaser C, Gavali S, Salibay CJ, Fireman B, Dekker CL. Lack of association between childhood immunizations and encephalitis in California, 1998-2008. Vaccine. 2012 Jan 05; 30(2):247-53. PMID: 22080172.
      View in: PubMed
    34. Williams SE, Pahud BA, Vellozzi C, Donofrio PD, Dekker CL, Halsey N, Klein NP, Baxter RP, Marchant CD, Larussa PS, Barnett ED, Tokars JI, McGeeney BE, Sparks RC, Aukes LL, Jakob K, Coronel S, Sejvar JJ, Slade BA, Edwards KM. Causality assessment of serious neurologic adverse events following 2009 H1N1 vaccination. Vaccine. 2011 Oct 26; 29(46):8302-8. PMID: 21893148.
      View in: PubMed
    35. Williams SE, Klein NP, Halsey N, Dekker CL, Baxter RP, Marchant CD, LaRussa PS, Sparks RC, Tokars JI, Pahud BA, Aukes L, Jakob K, Coronel S, Choi H, Slade BA, Edwards KM. Overview of the Clinical Consult Case Review of adverse events following immunization: Clinical Immunization Safety Assessment (CISA) network 2004-2009. Vaccine. 2011 Sep 16; 29(40):6920-7. PMID: 21801776.
      View in: PubMed
    36. Klein NP, Gidudu J, Qiang Y, Pahud B, Rowhani-Rahbar A, Baxter R, Dekker CL, Edwards KM, Halsey NA, Larussa P, Marchant C, Tokars JI, Destefano F. Developing the next generation of vaccinologists. Vaccine. 2011 Nov 21; 29(50):9296-7. PMID: 21510995.
      View in: PubMed
    37. Pahud BA, Glaser CA, Dekker CL, Arvin AM, Schmid DS. Varicella zoster disease of the central nervous system: epidemiological, clinical, and laboratory features 10 years after the introduction of the varicella vaccine. J Infect Dis. 2011 Feb 01; 203(3):316-23. PMID: 21177308.
      View in: PubMed
    38. Pahud BA, Greenhow TL, Piecuch B, Weintrub PS. Preterm neonates with candidal brain microabscesses: a case series. J Perinatol. 2009 Apr; 29(4):323-6. PMID: 19325555.
      View in: PubMed
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