Abatacept
"Abatacept" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Descriptor ID |
D000069594
|
MeSH Number(s) |
D12.776.124.486.485.114.580.225 D12.776.124.790.651.114.580.225 D12.776.377.715.548.114.580.225
|
Concept/Terms |
BMS 188667- BMS 188667
- 188667, BMS
- BMS-188667
- BMS188667
CTLA-4-Ig- CTLA-4-Ig
- CTLA4-Ig Immunoconjugate
- CTLA4 Ig Immunoconjugate
- Immunoconjugate, CTLA4-Ig
- CTLA4-Ig
- CTLA4-Fc
- Cytotoxic T Lymphocyte-associated Antigen 4-immunoglobulin
- Cytotoxic T Lymphocyte associated Antigen 4 immunoglobulin
|
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