 NF-E2-Related Factor 2
"NF-E2-Related Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
| Descriptor ID |
D051267
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| MeSH Number(s) |
D12.776.260.108.737 D12.776.930.127.737
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| Concept/Terms |
NF-E2-Related Factor 2- NF-E2-Related Factor 2
- NF E2 Related Factor 2
- Nuclear Factor E2-Related Factor 2
- Nuclear Factor E2 Related Factor 2
- Nfe2l2 Protein
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
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Below are MeSH descriptors whose meaning is more general than "NF-E2-Related Factor 2".
Below are MeSH descriptors whose meaning is more specific than "NF-E2-Related Factor 2".
This graph shows the total number of publications written about "NF-E2-Related Factor 2" by people in this website by year, and whether "NF-E2-Related Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "NF-E2-Related Factor 2" by people in Profiles.
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Liu J, Lickteig AJ, Zhang Y, Csanaky IL, Klaassen CD. Activation of Nrf2 decreases bile acid concentrations in livers of female mice. Xenobiotica. 2021 May; 51(5):605-615.
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Zhang Y, Lickteig AJ, Liu J, Csanaky IL, Klaassen CD. Effects of ablation and activation of Nrf2 on bile acid homeostasis in male mice. Toxicol Appl Pharmacol. 2020 09 15; 403:115170.
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Sampath V, Helbling D, Menden H, Dimmock D, Mulrooney NP, Murray JC, Dagle JM, Garland JS. Necrotizing Enterocolitis Is Not Associated With Sequence Variants in Antioxidant Response Genes in Premature Infants. J Pediatr Gastroenterol Nutr. 2016 Mar; 62(3):420-3.
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Sampath V, Garland JS, Helbling D, Dimmock D, Mulrooney NP, Simpson PM, Murray JC, Dagle JM. Antioxidant response genes sequence variants and BPD susceptibility in VLBW infants. Pediatr Res. 2015 Mar; 77(3):477-83.
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Permuth-Wey J, Chen YA, Tsai YY, Chen Z, Qu X, Lancaster JM, Stockwell H, Dagne G, Iversen E, Risch H, Barnholtz-Sloan J, Cunningham JM, Vierkant RA, Fridley BL, Sutphen R, McLaughlin J, Narod SA, Goode EL, Schildkraut JM, Fenstermacher D, Phelan CM, Sellers TA. Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk. Cancer Epidemiol Biomarkers Prev. 2011 Jun; 20(6):1131-45.
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Reisman SA, Csanaky IL, Aleksunes LM, Klaassen CD. Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. Toxicol Sci. 2009 May; 109(1):31-40.
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Reisman SA, Csanaky IL, Yeager RL, Klaassen CD. Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity. Toxicol Sci. 2009 May; 109(1):24-30.
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