 Epigenesis, Genetic
"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
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| MeSH Number(s) |
G05.355.315.203
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| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
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Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 4 | 7 | | 2014 | 2 | 5 | 7 | | 2015 | 4 | 5 | 9 | | 2016 | 1 | 2 | 3 | | 2017 | 2 | 4 | 6 | | 2018 | 0 | 3 | 3 | | 2019 | 3 | 4 | 7 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 2 | 3 | | 2025 | 0 | 3 | 3 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Marchi F, Shastri VM, Marrero RJ, Nguyen NHK, ?ttl A, Schade AK, Landwehr M, Krali O, Nordlund J, Ghavami M, Sckaff F, Mansinghka VK, Cao X, Slayton W, Starostik P, Cogle CR, Ribeiro RC, Rubnitz JE, Klco J, Elsayed A, Gamis AS, Triche TJ, Ries R, Kolb EA, Aplenc R, Alonzo T, Pounds S, Meshinchi S, Lamba JK. Epigenomic diagnosis and prognosis of Acute Myeloid Leukemia. Nat Commun. 2025 Jul 29; 16(1):6961.
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Shao X, Le Fur S, Cheung W, Belot MP, Perge K, Bouhours-Nouet N, Bensignor C, Levaillant L, Ge B, Kwan T, Lathrop M, Pastinen T, Bougn?res P. CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci. Sci Rep. 2025 May 08; 15(1):15999.
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Spector BL, Koseva B, McLennan R, Banerjee D, Lankachandra K, Bradley T, Selvarangan R, Grundberg E. Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19. BMC Med Genomics. 2025 Apr 01; 18(1):62.
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Guest EM, Kairalla JA, Devidas M, Hibbitts E, Carroll AJ, Heerema NA, Kubaney HR, August MA, Ramesh S, Yoo B, Farooqi MS, Pauly MG, Wechsler DS, Miles RR, Reid JM, Kihei CD, Gore L, Raetz EA, Hunger SP, Loh ML, Brown PA. Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children's Oncology Group trial AALL15P1. Haematologica. 2024 Dec 01; 109(12):3918-3927.
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Christiansen C, Potier L, Martin TC, Villica?a S, Castillo-Fernandez JE, Mangino M, Menni C, Tsai PC, Campbell PJ, Mullin S, Ordo?ana JR, Monteagudo O, Sachdev PS, Mather KA, Trollor JN, Pietilainen KH, Ollikainen M, Dalg?rd C, Kyvik K, Christensen K, van Dongen J, Willemsen G, Boomsma DI, Magnusson PKE, Pedersen NL, Wilson SG, Grundberg E, Spector TD, Bell JT. Enhanced resolution profiling in twins reveals differential methylation signatures of type 2 diabetes with links to its complications. EBioMedicine. 2024 May; 103:105096.
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Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z, Yotova V, Sindeaux R, Pramatarova A, Simon MM, Chen X, Groza C, Lougheed D, Gregoire R, Brownlee D, Boye C, Pique-Regi R, Li Y, He X, Bujold D, Pastinen T, Bourque G, Barreiro LB. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet. 2024 Mar; 56(3):408-419.
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Fu Q, Frick JM, O'Neil MF, Eller OC, Morris EM, Thyfault JP, Christianson JA, Lane RH. Early-life stress perturbs the epigenetics of Cd36 concurrent with adult onset of NAFLD in mice. Pediatr Res. 2023 Dec; 94(6):1942-1950.
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Spector BL, Harrell L, Sante D, Wyckoff GJ, Willig L. The methylome and cell-free DNA: current applications in medicine and pediatric disease. Pediatr Res. 2023 07; 94(1):89-95.
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Ke X, Huang Y, Fu Q, Majnik A, Sampath V, Lane RH. Adverse maternal environment alters Oprl1 variant expression in mouse hippocampus. Anat Rec (Hoboken). 2023 01; 306(1):162-175.
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Christiansen C, Tomlinson M, Eliot M, Nilsson E, Costeira R, Xia Y, Villica?a S, Mompeo O, Wells P, Castillo-Fernandez J, Potier L, Vohl MC, Tchernof A, Moustafa JE, Menni C, Steves CJ, Kelsey K, Ling C, Grundberg E, Small KS, Bell JT. Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers. Genome Med. 2022 07 18; 14(1):75.
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