 I-kappa B Proteins
"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
| Descriptor ID |
D020672
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| MeSH Number(s) |
D12.644.360.378 D12.776.260.420 D12.776.476.381 D12.776.930.326
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| Concept/Terms |
I-kappa B Proteins- I-kappa B Proteins
- I kappa B Proteins
- IkB DNA-Binding Proteins
- IkB DNA Binding Proteins
- I kappa B
- I-kappa B
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Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".
This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.
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Wu S, Walenkamp MJ, Lankester A, Bidlingmaier M, Wit JM, De Luca F. Growth hormone and insulin-like growth factor I insensitivity of fibroblasts isolated from a patient with an I{kappa}B{alpha} mutation. J Clin Endocrinol Metab. 2010 Mar; 95(3):1220-8.
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Wu S, De Luca F. Inhibition of the proteasomal function in chondrocytes down-regulates growth plate chondrogenesis and longitudinal bone growth. Endocrinology. 2006 Aug; 147(8):3761-8.
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