Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.

Descriptor ID	D016254
MeSH Number(s)	E05.393.420.601.550 G05.355.600.550 G05.365.590.575
Concept/Terms	Mutagenesis, Insertional Mutagenesis, Insertional Insertional Mutagenesis Sequence Insertion Sequence Insertion Insertion, Sequence Insertions, Sequence Sequence Insertions Viral Insertional Mutagenesis Viral Insertional Mutagenesis Insertional Mutagenesis, Viral Mutagenesis, Viral Insertional Linker-Insertion Mutagenesis Linker-Insertion Mutagenesis Linker Insertion Mutagenesis Mutagenesis, Linker-Insertion Gene Insertion Gene Insertion Gene Insertions Insertion, Gene Insertions, Gene Insertion Mutation Insertion Mutation Insertion Mutations Mutation, Insertion Mutations, Insertion Insertional Activation Insertional Activation Activation, Insertional Activations, Insertional Insertional Activations Mutagenesis, Cassette Mutagenesis, Cassette Cassette Mutagenesis

Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Insertional".

Below are MeSH descriptors whose meaning is related to "Mutagenesis, Insertional".

Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Insertional".