Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children.

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Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children.

van Haandel L, Goldman JL, Pearce RE, Leeder JS. Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children. Chem Res Toxicol. 2014 Feb 17; 27(2):211-8.

View in: PubMed

subject areas

Acetylcysteine
Anti-Infective Agents
Biomarkers
Biotransformation
Child
Child, Preschool
Chromatography, Liquid
Humans
Microsomes, Liver
Tandem Mass Spectrometry
Trimethoprim
Trimethoprim, Sulfamethoxazole Drug Combination

authors with profiles

J. Steven Leeder
Jennifer L. Goldman