Polyglutamic Acid
"Polyglutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide that is a homopolymer of glutamic acid.
Descriptor ID |
D011099
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MeSH Number(s) |
D12.125.067.625.700 D12.125.119.409.700 D12.644.748
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polyglutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Polyglutamic Acid".
This graph shows the total number of publications written about "Polyglutamic Acid" by people in this website by year, and whether "Polyglutamic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2011 | 2 | 0 | 2 |
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Below are the most recent publications written about "Polyglutamic Acid" by people in Profiles.
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Singh RK, van Haandel L, Kiptoo P, Becker ML, Siahaan TJ, Funk RS. Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model. Eur J Pharmacol. 2019 Jun 15; 853:264-274.
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van Haandel L, Becker ML, Williams TD, Leeder JS, Stobaugh JF. Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS. Bioanalysis. 2011 Dec; 3(24):2783-96.
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Becker ML, Gaedigk R, van Haandel L, Thomas B, Lasky A, Hoeltzel M, Dai H, Stobaugh J, Leeder JS. The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response. Arthritis Rheum. 2011 Jan; 63(1):276-85.
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Becker ML, van Haandel L, Gaedigk R, Lasky A, Hoeltzel M, Stobaugh J, Leeder JS. Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations. Arthritis Rheum. 2010 Jun; 62(6):1803-12.
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van Haandel L, Becker ML, Leeder JS, Williams TD, Stobaugh JF. A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells. Rapid Commun Mass Spectrom. 2009 Dec; 23(23):3693-702.
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