 Oncogenes
"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
| Descriptor ID |
D009857
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| MeSH Number(s) |
G05.360.340.024.340.375.500
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| Concept/Terms |
Oncogenes- Oncogenes
- Transforming Genes
- Transforming Gene
- Gene, Transforming
- Genes, Transforming
- Oncogene
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Below are MeSH descriptors whose meaning is more general than "Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Oncogenes".
This graph shows the total number of publications written about "Oncogenes" by people in this website by year, and whether "Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oncogenes" by people in Profiles.
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Kaida A, Yamamoto S, Parrales A, Young ED, Ranjan A, Alalem MA, Morita KI, Oikawa Y, Harada H, Ikeda T, Thomas SM, Diaz FJ, Iwakuma T. DNAJA1 promotes cancer metastasis through interaction with mutant p53. Oncogene. 2021 08; 40(31):5013-5025.
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Dempster JM, Pacini C, Pantel S, Behan FM, Green T, Krill-Burger J, Beaver CM, Younger ST, Zhivich V, Najgebauer H, Allen F, Gon?alves E, Shepherd R, Doench JG, Yusa K, Vazquez F, Parts L, Boehm JS, Golub TR, Hahn WC, Root DE, Garnett MJ, Tsherniak A, Iorio F. Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets. Nat Commun. 2019 12 20; 10(1):5817.
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Adhikari AS, Iwakuma T. Mutant p53 gain of oncogenic function: in vivo evidence, mechanism of action and its clinical implications. Fukuoka Igaku Zasshi. 2009 Jun; 100(6):217-28.
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McArthur CP, Wang Y, Heruth D, Gustafson S. Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53. Arch Oral Biol. 2001 Jun; 46(6):545-55.
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Forrest D, Curran T. Crossed signals: oncogenic transcription factors. Curr Opin Genet Dev. 1992 Feb; 2(1):19-27.
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Curran T. Nobel oncogenes. New Biol. 1989 Dec; 1(3):229-31.
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Curran T, Franza BR. Fos and Jun: the AP-1 connection. Cell. 1988 Nov 04; 55(3):395-7.
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Curran T, Rauscher FJ, Cohen DR, Franza BR. Beyond the second messenger: oncogenes and transcription factors. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:769-77.
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Stacey DW, Watson T, Kung HF, Curran T. Microinjection of transforming ras protein induces c-fos expression. Mol Cell Biol. 1987 Jan; 7(1):523-7.
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Sambucetti LC, Curran T. The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose. Science. 1986 Dec 12; 234(4782):1417-9.
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